• Send Us A Tip
  • Calling all Tech Writers
  • Advertise
Sunday, July 20, 2025
  • Login
TechStory
  • News
  • Crypto
  • Gadgets
  • Memes
  • Gaming
  • Cars
  • AI
  • Startups
  • Markets
  • How to
No Result
View All Result
  • News
  • Crypto
  • Gadgets
  • Memes
  • Gaming
  • Cars
  • AI
  • Startups
  • Markets
  • How to
No Result
View All Result
TechStory
No Result
View All Result
Home World

Fentanyl Vaccine: Potential “Game Changer” for the Opioid Epidemic

by Sneha Singh
November 21, 2022
in World
Reading Time: 3 mins read
0
Fentanyl
TwitterWhatsappLinkedin

According to a study, a new vaccine might stop lethal opioids from entering the brain. To prevent the harmful synthetic opioid fentanyl from entering the brain and producing its desired “high,” a brand-new vaccination has been created. The ground-breaking discovery may significantly affect the nation’s opioid epidemic by serving as a relapse prevention tool for opioid users trying to stop taking them. Opioid Use Disorder (OUD) is a curable disorder, according to a study.

You might also like

India Emerges as Global iPhone Hub: Apple Exports Hit $5 Bn in Just One Quarter

Weekly Business Updates: Everything from Byjus legal battle to the LAT Aerospace buzz

Weekly Startup Funding News: Indian startups raised $80 Mn this week; from Zuppa to CureFit

However, 80% of people who become dependent on it relapse. So a research team led by the University of Houston created the vaccination.

The findings, which were just published in the journal Pharmaceutics, could not be more pertinent or in demand. 

Fentanyl is not a natural opioid. It is a synthetic opioid that is 50 times more powerful and potent than heroin and 100 times more potent compared to morphine. It causes over 150 deaths every day. Depending on a person’s size, ingesting roughly 2 milligrams of fentanyl is likely lethal. 

 fentanyl

The fentanyl Vaccine works on the brain

“We believe these findings could significantly impact a severe problem plaguing society for years – opioid misuse. Our vaccine can generate anti-fentanyl antibodies that bind to the consumed fentanyl and prevent it from entering the brain, allowing it to be eliminated from the body via the kidneys. Thus, the individual will not feel the euphoric effects and can ‘get back on the wagon’ to sobriety,” said the study’s lead author Colin Haile.

He is a founding member of the UH Drug Discovery Institute and a research associate professor of psychology at UH and the Texas Institute for Measurement, Evaluation, and Statistics (TIMES).

Addition to street drugs

Due to its frequent addition to street drugs like cocaine and methamphetamine, other opioids like oxycodone and hydrocodone/acetaminophen tablets, and even fake benzodiazepines like Xanax and fentanyl pose a particularly severe hazard. In addition, these fentanyl-laced counterfeit medications increase the number of fentanyl overdoses in people who don’t typically use opioids.

“The anti-fentanyl antibodies were specific to fentanyl and a fentanyl derivative and did not cross-react with other opioids, such as morphine. So that means a vaccinated person would still be able to be treated for pain relief with other opioids,” Haile said.

The tested vaccination includes dmLT, an E. coli-derived adjuvant. A crucial element for the efficiency of anti-addiction vaccines is an adjuvant molecule, which increases the immune system’s reaction to vaccinations. The adjuvant, which partners created at the Tulane University School of Medicine, has proven essential to the vaccine’s effectiveness. 

Along with experts from Baylor College of Medicine and the Michael E. DeBakey Veteran’s Affairs Medical Center, Greg Cuny, the Joseph P. & Shirley Shipman Buckley Endowed Professor of Drug Discovery at the University of Houston College of Pharmacy, is also a member of the team.

The success of methadone, buprenorphine, and naltrexone, the current treatments for OUD, depends on the formulation, compliance, availability of the drugs, and the particular opioid that was mishandled.

The novel vaccination has the potential to be a “game changer,” according to Therese Kosten, professor of psychology and program director for UH’s Developmental, Cognitive & Behavioral Neuroscience department.

“Fentanyl use and overdose is a particular treatment challenge that is not adequately addressed with current medications because its pharmacodynamics and managing acute overdose with the short-acting naloxone are not as effective as multiple doses of naloxone are often needed to reverse fentanyl’s fatal effects,” said Kosten.

Tags: BrainFentanyl VaccineOpioidvaccine
Tweet54SendShare15
Previous Post

Moody’s to shutdown analytics business in China; Layoff employees

Next Post

Who lost cash in FTX crypto crash? Top investor who lost their money

Sneha Singh

Sneha is a skilled writer with a passion for uncovering the latest stories and breaking news. She has written for a variety of publications, covering topics ranging from politics and business to entertainment and sports.

Recommended For You

India Emerges as Global iPhone Hub: Apple Exports Hit $5 Bn in Just One Quarter

by Ishaan Negi
July 19, 2025
0
Apple to pay up to $500 million to iPhone users after judge nixes final appeal

India's ambition to become a global electronics powerhouse just got a significant boost. Apple has exported over $5 billion worth of iPhones from India during the April–June quarter...

Read more

Weekly Business Updates: Everything from Byjus legal battle to the LAT Aerospace buzz

by Ishaan Negi
July 19, 2025
0
Weekly Business News: Top business updates in this week

From courtrooms to boardrooms, India’s digital and entrepreneurial landscape is buzzing with action. In this article, we explore six major developments—from regulatory showdowns and billion-dollar lawsuits to strategic...

Read more

Weekly Startup Funding News: Indian startups raised $80 Mn this week; from Zuppa to CureFit

by Ishaan Negi
July 19, 2025
0
Weekly Startup Funding News: Indian startups raised $196 Mn this week; from Emiza to Leap

In this article, we delve into the key highlights, trends, and developments from India’s startup ecosystem between July 14 and July 19, 2025 — a week marked by...

Read more
Next Post
FTX

Who lost cash in FTX crypto crash? Top investor who lost their money

Please login to join discussion

Techstory

Tech and Business News from around the world. Follow along for latest in the world of Tech, AI, Crypto, EVs, Business Personalities and more.
reach us at [email protected]

Advertise With Us

Reach out at - [email protected]

BROWSE BY TAG

#Crypto #howto 2024 acquisition AI amazon Apple Artificial Intelligence bitcoin Business China cryptocurrency e-commerce electric vehicles Elon Musk Ethereum facebook funding Gaming Google India Instagram Investment ios iPhone IPO Market Markets Meta Microsoft News NFT samsung Social Media SpaceX startup startups tech technology Tesla TikTok trend trending twitter US

© 2024 Techstory.in

No Result
View All Result
  • News
  • Crypto
  • Gadgets
  • Memes
  • Gaming
  • Cars
  • AI
  • Startups
  • Markets
  • How to

© 2024 Techstory.in

Welcome Back!

Login to your account below

Forgotten Password?

Retrieve your password

Please enter your username or email address to reset your password.

Log In
Are you sure want to unlock this post?
Unlock left : 0
Are you sure want to cancel subscription?